Published Results Support ALDH2 inhibition for Treating Substance Use Disorder

Published Neurobiologic Model of Addiction                                              Read Article

Published Mechanism of Action                                                                  Read Article 

ANS-6637 Prevents Dopamine Surge which is Common to All Addiction


ANS-6637 is a selective ALDH2 Inhibitor that prevents pathophysiologic dopamine surge and associated craving without changes to basal dopamine. This profile, which prevents craving and drug seeking behavior, has the potential to be used as pharmacotherapy for any substance and behavior based addiction.