Published Neurobiologic Model of Addiction                                  Read Article

Dopamine Surge Drives Craving NOT Pleasure                                       

People, Places and Paraphernalia Cause a Dopamine Surge which Causes

                                                     Craving and Leads to Use and Relapse 

Preventing Dopamine Surge which is Common to All Addiction


Selective ALDH2 Inhibitor that prevents pathophysiologic dopamine surge and associated craving without changes to basal dopamine. This profile, which prevents craving and drug seeking behavior, has the potential to be used as pharmacotherapy for any substance and behavior based addiction.

Published Mechanism of Action                                                    Read Article